Month: June 2021

Although there are several methods for labeling and tracking RNA inside living cells, they lean heavily toward one side or another of a vexing tradeoff. At one extreme, there are labels that emit a strong signal and perturb mRNA activity. At the other extreme, there are labels that preserve natural mRNA activity and emit a

|Sponsored| I need this quilt finished—fast! Did the baby arrive a week early? Are you simply OVER feeling guilty about that stack of unfinished quilt tops? Or maybe you have a new machine, and want to a few practice projects to build your confidence! The point is, you’re interested in finishing a quilt FAST! We’re here

Source: Life Science Animation Close at the heels of the FDA’s conditional approval the new drug for Alzheimer’s disease, aducanumab, that acts by reducing soluble and insoluble β amyloid, a new study led by scientists at the University of Cincinnati (UC) in collaboration with the Karolinska Institute in Sweden, sheds new light on the pathological

Medulloblastoma is a brain tumor of the cerebellum. This fast-growing tumor can spread to other areas of the brain and spinal cord through cerebrospinal fluid (CSF). Metastasis to the lining of the brain or spinal cord is responsible for virtually all deaths from the disease. Now, new research led by the Keck School of Medicine

Immunologists at McMaster University say they have discovered a previously unknown mechanism which acts like a spider web, trapping and killing pathogens such as influenza or SARS-CoV-2. The researchers have found that neutrophils, the most abundant white blood cells in the human body, explode when they bind to such pathogens coated in antibodies and release

Researchers at McMaster University have developed a form of cancer immunotherapy that uses cancer-killing natural killer (NK) cells genetically engineered outside the body to target and destroy cancer cells, including solid tumor types. Their in vitro studies showed that these chimeric antigen receptor (CAR)-engineered NK cells can differentiate between cancer cells and healthy cells that

Debby Brown joins the show to encourage us to relax with our quilting. She feels that quilting should feel like a warm hug and we love it! In our Fine Finishes segment, Proptologist Jay Duckworth joins the crew—and makes them cry! He created commemorative medals for our sewing machines so future generations know that they

If you know whether a valuable product will continue to be readily available, you may need to do more than glance at retailer’s shelves or a distributor’s loading docks. You may want to examine a factory’s assembly lines. The desire to look all the way back to the start of a supply chain is what

Membranes, which support a wide swath of upstream and downstream bioprocessing, have evolved along with biopharma’s needs for throughput, timeliness, and quality. A recent paper by Andrew Zydney, PhD, the Bayard D. Kunkle chair and professor of chemical engineering at  Pennsylvania State University, observes that for membranes to continue in this role they must improve

Synthetic biology, biofoundries, and AI modeling could make vaccine production more sustainable and better prepare industry for pandemics, say some researchers. Until last year, vaccine manufacturing had not changed much in decades in terms of the technology the production methods used. The COVID-19 pandemic led to an entirely new manufacturing landscape. Efforts to develop and

While it may seem intuitive that stress can increase the rate at which hair turns gray, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons is the first to offer quantitative evidence linking psychological stress to graying hair in humans and indicates hair color may be restored upon elimination of

Inflammatory bowel disease (IBD) is a broad term that describes conditions characterized by chronic inflammation of the gastrointestinal tract. The two most common inflammatory bowel diseases are ulcerative colitis and Crohn’s disease. Several types of medications may be used to treat IBD such as aminosalicylates, corticosteroids (such as prednisone), immunomodulators, and “biologics.” Now, researchers from

Element Biosciences said today it completed a $276 million Series C financing whose proceeds are intended to fund the launch of the company’s next-generation DNA sequencing platform as well as scale its commercial operation. The latest financing accounts for more than half of Element’s total capital raised, bringing that total to approximately $400 million. Element

Researchers headed by a team at Columbia University Vagelos College of Physicians and Surgeons have linked distinct patterns of genetic mutations with obsessive-compulsive disorder (OCD) in humans. Reporting in Nature Neuroscience on their analysis of exome sequencing data from more than 1,000 individuals with OCD, the scientists say their findings “… support a contribution of