Researchers at UCL and MRC London Institute of Medical Sciences have demonstrated that reducing naturally occurring errors in protein synthesis improves both health and lifespan in different model organisms. The findings, reproduced in yeast, roundworms, and fruit flies, are the first to demonstrate a direct link between fewer protein mistakes and longevity. The study also
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Researchers are focusing on several major areas to improve cancer immunotherapy. Now, a team at Kyoto University report they have developed a synthetic molecule that can provide energy to anticancer immune cells, increasing their numbers and improving their longevity. Their findings are published in the journal Cell Chemical Biology in a paper titled, “Targeted epigenetic
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In the words of the French artist Henri Matisse, “An artist is an explorer.” Whether that exploration begins with formal art education in the classroom, spontaneous sketching in a travel journal, experimenting in your studio, or by merely noticing the flora and fauna around them, many art quilters are known to be deeply moved by nature. Today we’ll be exploring that link between the art we create and the environment in which we live
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After 14 years of stagnation, the long-defunct Hearst estate became the subject of a bidding war today — landing a $63.1 million offer. The seemingly unsellable home was set to sell for $47 million to Los Angeles-based investment company Berggruen Holdings, pending an auction where overbids were possible — and today’s auction did not disappoint.
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Smarter” manufacturing control systems are needed to cope with the increased use of outsourced production and multi-product facilities, according to new research. The study, by Sagnik Mitra, a doctoral researcher, and Ganti S. Murthy, PhD, professor, at the Indian Institute of Technology in Indore, examined whether established process control technologies are a good fit for modern biopharmaceutical
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Massachusetts Institute of Technology (MIT) engineers, working in collaboration with scientists at Cancer Research UK Manchester Institute, have developed a new way to grow pancreatic “organoids”—tiny replicas of the pancreas—from either healthy or cancerous pancreatic cells. Using a specialized synthetic hydrogel scaffold to mimic the extracellular environment, the researchers were able to grow tiny pancreatic
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Inspired by the natural bonding between a class of potent local anesthetics called site-1 sodium channel blockers (S1SCBs) and peptide sequences on the sodium channel in the nerve cell membrane, scientists at Boston Children’s Hospital and Harvard Medical School, have developed a self-assembling delivery system that releases the anesthetic over a prolonged period. S1SCBs such
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Dementia is the loss of cognitive functioning—thinking, remembering, and reasoning—to such an extent that it interferes with a person’s daily life and activities. To diagnose dementia, doctors first assess whether a person has an underlying, potentially treatable, condition that may relate to cognitive difficulties. A physical exam may be performed to measure blood pressure and
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A clinical trial conducted at the University of North Carolina Lineberger Comprehensive Cancer Center and Johns Hopkins Sidney Kimmel Comprehensive Cancer Center found that high-dose cytarabine followed by subsequent immunotherapy treatment with pembrolizumab benefited patients with resistant or relapsed acute myeloid leukemia (AML), a highly aggressive cancer. The findings (“Phase II Trial of Pembrolizumab after
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Editor’s Note: With so much market volatility, stay on top of daily news! Get caught up in minutes with our speedy summary of today’s must-read news and expert opinions. Sign up here! (Kitco News) – Gold and silver prices are weaker in early U.S. trading Monday, as buyers are timid to start the trading week due
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Humanigen is vowing to continue pursuing approvals for lenzilumab following the FDA’s rejection of its application for emergency use authorization (EUA) of the antibody as a treatment for patients hospitalized with COVID-19—a setback that has sent the company’s stock plunging more than 50%. The FDA stated in a letter that it was unable to conclude
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Scanning electron micrograph of methicillin-resistant Staphylococcus aureus (MRSA) bacteria being engulfed by a neutrophil [National Institute of Allergy and Infectious Diseases, National Institutes of Health] Research has found that, similar to a spider trapping its prey, the immune system’s neutrophil and macrophage cells can cooperate to capture and “eat” bacteria. Researchers at the Vanderbilt Institute
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