Month: August 2021

“Cobra Kai” fans can live like Daniel LaRusso in this Georgia mansion. The mysterious new owners of the 9,200-square-foot mansion that served as the LaRusso family house in “Cobra Kai” Seasons 1 through 3 plan to turn it into an Airbnb rental, according to multiple reports. In the YouTube-turned-Netflix-show — based on the iconic “Karate
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The Genetic Burden of Osteoarthritis. [Cindy Boer] Osteoarthritis is the most common form of arthritis. Some people call it degenerative joint disease or “wear and tear” arthritis and it occurs most frequently in the hands, hips, and knees. There are no curative treatments available and further understanding of disease cause is needed. Now, an international
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An international team of scientists reports that the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth. They say their study (“A cancer ubiquitome landscape identifies metabolic reprogramming as target of Parkin tumor
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A University of Pittsburgh (Pitt) School of Medicine-led team has identified neuroinflammation as the key driver of the spread of pathologically misfolded proteins in the brain, and a cause of cognitive impairment in patients with Alzheimer’s disease. Using positron emission tomography imaging, the researchers have, for the first time, shown in living patients that neuroinflammation—activation
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Sarah Fielke’s quilts seem to burst with color and life. The Australian quilter, teacher, author, and fabric designer is not afraid to mix colors, patterns, block styles, and methods to create happy quilts that seem to pop right off the wall or bed. “The style of the quilts is entirely my own aesthetic. My quilts
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A West Village townhouse at 30 Grove St. that was on the market for $28 million is in contract. If it closes, it is slated to be the highest sale in the glitzy neighborhood. The 5,800-square-foot home underwent a six-year renovation overseen by designers Mariette and Brooke Gomez. The listing broker was Jonathan Isaacs of
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Cristina Puig-Saus, PhD, and Daniel Shin, MD, PhD, from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of CAR T-cell therapy as a treatment for people with acral, mucosal, and uveal melanomas. The three-year, translational
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Tissue engineering aims to fabricate functional tissue for applications in regenerative medicine and drug testing. The most widely used bioprinting method is extrusion-based bioprinting, in which inks are dispensed continuously from nozzles and deposited along digitally defined paths to fabricate 3D structures layer by layer. However, one of the challenges of this method is the
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New research from Japan shows hamsters inoculated with spike gene mutants that lack the protease cleavage site are resistant to subsequent infection with both the parent strain and emerging alpha (UK/B.1.1.7) and gamma (Brazil/P.1) SARS-CoV-2 variants. “SARS-CoV-2 spike gene mutants may be used as immunogens for live-attenuated vaccines, similar to the current yellow fever vaccine,”
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