The American Association for Cancer Research (AACR) annual meeting kicked off (virtually) this past weekend. On the first morning of the meeting, the synthetic biology company Synlogic presented data from the clinical trial testing their immunotherapy drug SYNB1891. The drug, a living biotherapeutic consisting of engineered bacteria that are injected intratumorally, is being developed for
Neurons run on calcium, which plays a dual role as a charge carrier and an intracellular messenger. Calcium signals regulate various developmental processes and have a key role in apoptosis, neurotransmitter release, and membrane excitability; calcium is also involved in memory formation, metabolism, and cell growth—making it quite the multitasker. Now using animal models, researchers
Subscribe to Kitco Roundtable on iTunes The wide degree of speculation that is needed to author a preliminary feasibility study and other economic documents is not clear to the general investor, said Douglas Silver, CEO of Balfour Holdings. On Friday Silver joined editor Neils Christensen, Kitco correspondent Paul Harris and mining audiences manager Michael McCrae
For the past year, Times Square has been widely depicted as a deserted ghost of its former self. But people who love the “Crossroads of the World” even without Broadway continue to bring it back to life. Pedestrian counts in the Broadway-Seventh Avenue Bowtie between West 42nd and 47th streets are on the upswing yet
[embedded content] (Kitco News) The second quarter is already looking better for gold. The precious metal was up almost $50 dollars during the first week of April as it moved past its key resistance level of $1,750. But what happens next is critical — can gold finally hold above this level as analysts cite strength
As protests broke out across the country in the name of Black Lives Matter, the group’s co-founder went on a real estate-buying binge, snagging four high-end homes for $3.2 million in the US alone, according to property records. Patrisse Khan-Cullors, 37, also eyed property in the Bahamas at an ultra-exclusive resort where Justin Timberlake and
Oracle co-founder Larry Ellison just expanded his impressive $1 billion property portfolio by dropping $80 million on an oceanfront compound in North Palm Beach. Ellison bought the six-acre Florida estate from hedge-fund manager Gabe Hoffman, the founder of Accipiter Capital Management, above the $79.5 million asking price. The compound features more than 520 feet of
We need to help Kary Brittingham. A rogue bandit in the night must have entered her home and stolen all of the televisions because girlfriend is clearly not watching the current season of Real Housewives of Dallas. Kary joined RHOD in 2019 and was actually brought on as a friend of D’Andra Simmons. Thanks to
Patrisse Khan-Cullors, the leader of Black Lives Matter and a self-described Marxist, recently purchased a $1.4 million home in an exclusive Los Angeles neighborhood where the vast majority of residents are white, according to reports. The home, which features three bedrooms and three bathrooms, is nestled in Topanga Canyon and has a separate guesthouse on
(Kitco News) Gold has a chance to break above its key resistance level of $1,750 an ounce next week. Here’s what investors need to watch, according to analysts. The yellow metal had a very decent start to the second quarter, with prices up around 1% on the week. June Comex gold futures last traded at
Home is where the heart is, indeed. Prince Philip was only 26 years old when he married Queen Elizabeth II on November 20, 1947. In their nearly 74-year-long marriage, he was his wife and sovereign’s biggest supporter and lived a life of public service. Prince Philip, who died Friday morning at the age of 99,
Scientists led by a team at the Whitehead Institute have developed a new gene editing technology, called CRISPRoff, which can be used to control gene expression with high specificity, while leaving the sequence of the DNA unchanged. Utilizing a programmable, epigenetic memory writer protein to silence gene expression, CRISPRoff is a highly specific method that
A study of the human antibody response to the tick-borne encephalitis (TBE) virus reveals that it is dominated by ineffective antibodies. Occasionally, however, a few antibodies appear that are extremely potent. Now that potent antibodies have been discovered, and their structures determined, the prospects for targeting the TBE virus suddenly look much better. TBE, which
Zebrafish can heal their damaged hearts. Humans hearts retain scars of earlier injuries. In a new article published in the journal Science, titled “Krüppel-like factor 1 is a core cardiomyogenic trigger in zebrafish,” scientists from the Victor Chang Cardiac Research Institute in Sydney report finding a new genetic switch that could help damaged human heart
Before drugs can go into clinical trials to establish their efficacy, they must go through rigorous testing to demonstrate that they do no harm. A new study reports a way to make cell cultures respond more like normal cells. Culturing cells in this new method that uses a modified serum, will allow drugs to be
The first, complete, telomere-to-telomere sequence of a human autosome has been completed. The sequence of chromosome 8 not only fills in the gap of more than three million bases missing from the current reference genome, but its DNA content and arrangement are of interest in an evolutionary context, in several immune and developmental disorders, and
Current approaches to diagnosing and treating depressive disorders are based largely on trial and error, but a newly reported study by a team at Indiana University School of Medicine has shed new light on the biological basis of mood disorders. Through their research, reported in Molecular Psychiatry, the team has developed a blood test for
Apply the following to make your franchise organization thrive. April 9, 2021 4 min read Opinions expressed by Entrepreneur contributors are their own. The following is an excerpt from Franchise Bible: How to Buy a Franchise or Franchise Your Own Business, Ninth Edition, which will be released April 20 through Entrepreneur Press. Pre-order now via Amazon | Barnes
Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive muscle degeneration and weakness due to the alterations of a protein called dystrophin that helps keep muscle cells intact. Until recently, boys with DMD usually did not survive much beyond their teen years. Advances in cardiac and respiratory care have increased life expectancy and
All he does is win. DJ Khaled must be “on one” after unloading his sprawling Los Angeles mansion for $12.5 million — about $2.6 million more than he paid for it in 2016. The Grammy Award-winning musician and producer sold the six-bedroom, eight-bathroom palace to Beverly Hills-based plastic surgeon David Amron and his wife Jessica,
[embedded content] U.S. Treasury Secretary Janet Yellen has proposed a global minimum corporate tax rate for large companies. “We’re working with G20 nations to agree to a global minimum corporate tax rate that can stop the race to the bottom. Together, we can use the global minimum tax to make sure that the global economy
Start spreading the news: The townhouse that formerly belonged to the late CBS anchor Walter Cronkite has hit the market for $7.7 million. The sellers, Joseph Faccibene and Mary Kay Coyle, bought the home at 519 E. 84th St., between York and East End avenues, in 1999. Cronkite’s fan mail was still delivered to the
Steve Jobs spent over a decade trying to demolish his Woodside, California mansion — which he would eventually succeed in doing in 2011 during the final year of his life. But before the historic estate was destroyed, photographer Jonathan Haeber — who dedicates his free time to shooting abandoned homes — was able to cross
Moroccan-born New York rapper French Montana is living it up in a $50 million extravagant penthouse at the Casa Hotel and Residences, at 70 W. 45th St. The Theater District skypad would be perfect on the set of a Kardashian reality TV show, but Montana’s relationship with Khloe Kardashian is long over, though the two remain friends. (It was
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